Founded in 1958, the Annenberg School for Communication at the University of Pennsylvania offers students a firm grounding in various approaches to the study of communication and its methods, drawn from both the humanities and the social sciences. It is an intellectual common market built on more than 40 years of interdisciplinary dialogue. The School houses communication theorists and researchers, including social scientists, historians and critics. The M.A.C. and Ph.D. degree programs prepare students to make professional contributions to communication scholarship, research and policy. The School also houses the Annenberg Public Policy Center, which conducts and disseminates research, hosts lectures and conferences, and convenes roundtable discussions that highlight important questions about the intersection of media, communication and public policy.

Founded in 1971 with support from Ambassador Walter H. Annenberg, the Annenberg School for Communication & Journalism at the University of Southern California is located in Los Angeles.  It fosters dynamic synergies and multidisciplinary approaches to the study of communication and journalism through unparalleled access to the nation's and the world's entertainment, media and technology industries. Today, with more than 80  full-time faculty members and 120 adjunct professors, more than 2,200 undergraduate and graduate students, and dozens of research and public interest projects and programs, including the Norman Lear Center and the Knight Digital Media Center, USC Annenberg has become a center for discussion among scholars and professionals in journalism, communication, public policy, media and education. 

The Annenberg Center for Health Sciences at the Eisenhower Medical Center in Rancho Mirage, California, was founded in 1981 as a distinguished forum for the examination of healthcare issues and the advancement of science and medicine. The Center creates and delivers health education programs; over the years it has reached hundreds of thousands of healthcare professionals around the world through its unique conference and telecommunication facilities.

The Annenberg Public Policy Center of the University of Pennsylvania was established in 1994. Through offices in Philadelphia and Washington, D.C., it conducts and disseminates research, hosts lectures and conferences, and convenes discussions on the critical intersection of media, communication and public policy. Research focuses on questions and issues in political communication, information and society, media and the developing child, health communication, and adolescent risk. 

The Annenberg Public Policy Center has developed such initiatives as FactCheck.org, which aims to increase public knowledge and understanding by monitoring the factual accuracy of political dialogue, and the National Annenberg Election Survey, the nation's largest academic election poll.